These pick up lines are highly contagious — and totally irresistible! If you’re looking to infect someone with a serious case of butterflies, these Infection pick up lines will spread smiles faster than a viral meme.
Whether you’re a med student, a healthcare worker, or just love some delightfully twisted humor, this list is the perfect mix of flirty and funny.
From feverishly clever wordplay to dangerously smooth one-liners, these pick up lines are anything but sterile. They’re ideal for those who like their flirting with a dose of sass and science.
1. Bold Infection Rizz Lines 🔥

- Are you a virus? Because you’ve infected my thoughts 24/7.
- I must be a pathogen because I can’t resist invading your personal space.
- You’re like COVID—once I catch you, I can’t let go.
- Is your name Delta? Because you’re a dominant variant in my mind.
- I don’t need a vaccine—I’m immune to everyone but you.
- Are you a fever? Because you’re making me hot and delirious.
- You’re like a superbug—no matter what I do, I can’t get rid of you.
- I should quarantine myself—because being near you is too contagious.
- Are you an outbreak? Because you’re spreading fast in my heart.
- You must be a rare strain—because I’ve never felt this way before.
- I’d let you infect me any day.
- You’re like the flu—sudden, intense, and impossible to ignore.
- Is your love airborne? Because I think I just caught it.
- Warning: Prolonged exposure to you may cause heart palpitations.
- I don’t need a cure—I want this infection to last forever.
🔥 Tip: Deliver these with smirking confidence—weak delivery makes them creepy!
2. Cute Infection Pick Up Lines for Her 💘

- Are you a cold? Because you’ve got me sneezing (on love).
- You’re like a mild fever—warm, cozy, and hard to shake.
- Is your name Vitamin C? Because you boost my immune system.
- Are you a healing wound? Because every time I see you, I feel better.
- You must be an antibody—because you destroy all my bad moods.
- Are you a vaccine? Because you just cured my loneliness.
- You’re like chicken soup—warm, comforting, and exactly what I need.
- Is your love a placebo? Because just thinking about you makes me happy.
- Are you a band-aid? Because you fix all my heart’s boo-boos.
- You must be a probiotic—because you bring balance to my life.
- Are you a doctor? Because you just diagnosed me with a crush.
- You’re like a healing touch—gentle and exactly what I needed.
- Is your smile contagious? Because I can’t stop catching it.
- You must be a miracle cure—because I’m addicted to you.
- Are you a hospital? Because you’ve got me checking in forever.
💘 Warning: Use responsibly—may cause excessive blushing.
3. Funny Infection Pick Up Lines 😂

- Are you a zombie virus? Because you’re turning me into a walking simp.
- Is your love a side effect? Because I can’t stop feeling it.
- Are you a plague doctor? Because you’ve got me masked up (in love).
- You must be a fungal infection—because you’re growing on me.
- Are you a common cold? Because I can’t seem to shake you.
- Is your name Omicron? Because you’re all I’m thinking about.
- You’re like pink eye—irresistible but slightly embarrassing.
- Are you a stomach bug? Because you’re making me feel butterflies.
- You must be a parasite—because I can’t live without you.
- Is your love strep throat? Because it’s hard to swallow how much I like you.
- Are you a lab experiment? Because you’re driving me wild.
- You’re like a bad rash—annoyingly persistent but kinda cute.
- Is your name Patient Zero? Because you started this outbreak of love.
- You must be a quarantine—because I can’t leave you alone.
- Are you a medical bill? Because you’re taking all my money (and my heart).
😂 Tip: If they laugh, you’re already winning.
4. fearless Infection Rizz Lines ⚡
- Are you a pandemic? Because the whole world should know about you.
- You must be antibiotic-resistant—because nothing can tear me away from you.
- Is your love a biohazard? Because I’m ready to risk it all.
- Are you a surgical mask? Because I can’t breathe without you.
- You’re like a virus mutation—unpredictable and dangerously attractive.
- Is your name Pfizer? Because you just gave me the best side effects.
- You must be a CDC warning—because you’re too hot to handle.
- Are you a ventilator? Because you take my breath away.
- You’re like a global outbreak—impossible to ignore.
- Is your love a symptom? Because I’m showing all the signs.
- Are you a lab leak? Because you’re spreading fast in my heart.
- You must be a contagion—because one look and I’m hooked.
- Is your name Asymptomatic? Because I can’t tell if you’re into me.
- You’re like a vaccine passport—without you, I’m going nowhere.
- Are you a spike protein? Because you’ve locked onto my heart.
⚡ Warning: Use with caution—may cause instant attraction.
5. Science Nerd Infection Lines 🧪
- Are you mitochondria? Because you’re the powerhouse of my heart.
- Is your love a double helix? Because we’re a perfect match.
- You must be a stem cell—because you’re changing my life.
- Are you a microscope? Because I can’t take my eyes off you.
- You’re like a Petri dish—culturing all my love for you.
- Is your name CRISPR? Because you’ve edited my heart.
- You must be a neurotransmitter—because you’re giving me all the right signals.
- Are you a lab coat? Because you make me look smart.
- You’re like a chemical reaction—exothermic and explosive.
- Is your love a hypothesis? Because I want to test it every day.
- Are you a centrifuge? Because you’re spinning me right round.
- You must be a DNA strand—because you complete me.
- Is your name ATP? Because you give me energy.
- You’re like a lab report—detailed and impossible to resist.
- Are you a scientific theory? Because I believe in you.
🧪 Tip: Works best on fellow nerds—drop these in a science class or bio lab!
6. Flirty Infection Lines for Texting 📱
- Are you WiFi? Because I’m feeling a strong connection.
- Is your name Google? Because you’re everything I’ve been searching for.
- You must be a pop-up ad—because I can’t close this tab (on you).
- Are you a software update? Because you’ve upgraded my heart.
- You’re like my phone battery—I can’t last a day without you.
- Is your love a glitch? Because you’re all I see.
- You must be a charger—because you bring me back to life.
- Are you a notification? Because you light up my screen (and my life).
- You’re like autocorrect—always fixing my mistakes.
- Is your name Siri? Because I’m asking you out.
- Are you a screenshot? Because I can’t forget you.
- You must be a meme—because I can’t stop thinking about you.
- Is your love a filter? Because you make everything better.
- You’re like my home screen—always on my mind.
- Are you a password? Because you’re hard to crack (but worth it).
📱 Tip: Send with a winky face for extra rizz.
7. Cheesy Infection Pick Up Lines 🧀
- Are you a bacteria? Because you’re multiplying in my heart.
- Is your name E. Coli? Because you’re making me feel funny.
- You must be a virus—because you’re crashing my system (in a good way).
- Are you a white blood cell? Because you’re fighting for my heart.
- You’re like a common cold—annoyingly cute.
- Is your love a vaccine trial? Because I’m willing to test it.
- You must be a fever dream—because you’re too good to be true.
- Are you a stethoscope? Because you’re listening to my heartbeat.
- You’re like a medical chart—complicated but fascinating.
- Is your name ICU? Because I’m checking in forever.
- Are you a prescription? Because I need you daily.
- You must be a blood test—because you’re getting under my skin.
- Is your love a diagnosis? Because I’ve got it bad.
- You’re like a hospital gown—always leaving me exposed.
- Are you a doctor’s note? Because you’ve got me excused from loneliness.
8. Smooth Infection Rizz for Guys 🎩
- Are you an antibody? Because you’re the perfect match for me.
- Is your name Penicillin? Because you just cured my sadness.
- You must be a vaccine—because you’re my only shot at love.
- Are you a heartbeat? Because you’re the rhythm of my life.
- You’re like a medical miracle—one in a million.
- Is your love a clinical trial? Because I’m willing to take the risk.
- You must be a surgeon—because you’ve got my heart in your hands.
- Are you a blood donor? Because you’ve given me life.
- You’re like a first aid kit—always saving me.
- Is your name ER? Because you’re an emergency (for my heart).
- Are you a thermometer? Because you’re making my temperature rise.
- You must be a medical breakthrough—because I’ve never felt this before.
- Is your love a bandage? Because you heal all my wounds.
- You’re like a doctor’s order—non-negotiable.
- Are you a health inspector? Because you’ve got me passing with flying colors.
🎩 Tip: Pair with gentle eye contact for maximum effect.
9. Playful Infection Lines for Girls 💃
- Are you a vaccine? Because I can’t resist your doses.
- Is your name ICU? Because I’m checking you out.
- You must be a fever—because you’re making me sweat.
- Are you a lab result? Because you’re positive (for love).
- You’re like a medical mystery—I can’t figure you out (but I love trying).
- Is your love a quarantine? Because I’m stuck on you.
- You must be a surgeon—because you’re cutting straight to my heart.
- Are you a stethoscope? Because you’re listening to my deepest feelings.
- You’re like a prescription—exactly what I needed.
- Is your name Dr. Love? Because I need a check-up.
- Are you a blood type? Because you’re my perfect match.
- You must be a medical school—because you’ve got me studying you.
- Is your love a diagnosis? Because I’m infected.
- You’re like a hospital bed—I never want to leave.
- Are you a nurse? Because you’ve got me feeling better already.
💃 Warning: May cause uncontrollable flirting.
10. Wildcard Infection Rizz Lines 🎲
- Are you a zombie apocalypse? Because I’d survive just for you.
- Is your love a bio-weapon? Because I’m defenseless.
- You must be a CDC alert—because I can’t ignore you.
- Are you a lab rat? Because I’m experimenting with love.
- You’re like a pandemic—world-changing and unforgettable.
- Is your name Patient Zero? Because you started this love outbreak.
- You must be a hazmat suit—because you’re protecting my heart.
- Are you a quarantine zone? Because I’m locked in (on you).
- You’re like a virus scan—checking me out thoroughly.
- Is your love a clinical study? Because I’m your biggest subject.
- Are you a medical bill? Because you’re worth every penny.
- You must be a lab leak—because you’re spreading fast in my heart.
- Is your name Asymptomatic? Because I can’t tell if you’re flirting.
- You’re like a vaccine side effect—unexpected but worth it.
- Are you a hospital gown? Because I’m falling for you fast.
🎲 Tip: Best used when they least expect it—shock rizz works!
How to Use These Infection Pick Up Lines
- IRL: Drop them with confidence and a smirk—delivery is key!
- Texting/DMs: Add a funny GIF or emoji to keep it playful.
- First dates: Gauge their humor first—cheesy works, creepy doesn’t.
FAQs:
Do infection pick-up lines actually work?
If delivered right—yes! They’re funny, unexpected, and show confidence.
Aren’t these too cheesy?
Embrace the cringe! Cheese = charm when done right.
Where’s the best place to use these?
Texting, parties, or flirty convos—avoid serious settings.
What if they don’t get the joke?
Laugh it off! “Too scientific? How about this…” and switch gears.
Can I modify these lines?
Absolutely! Personalize them for better rizz.
Rizz Recap: 7 Most Infectious Lines
- “Are you a virus? Because you’ve infected my thoughts 24/7.”
- “You must be antibiotic-resistant—because nothing can tear me away.”
- “Is your love airborne? Because I think I just caught it.”
- “Are you a vaccine? Because you just cured my loneliness.”
- “You’re like pink eye—irresistible but slightly embarrassing.”
- “Is your name Pfizer? Because you gave me the best side effects.”
- “Are you a zombie virus? Because you’re turning me into a walking simp.”
Call to Action (CTA)
Which line was your favorite? Drop it in the comments or DM us your own infection rizz! Let’s spread the love (and the laughs). 💌🔥
Conclusion
Infection pick-up lines are playful, bold, and just the right amount of weird to make flirting fun.
Whether you’re going for cheesy, fearless, or smooth, these lines guarantee a reaction.